Fine lines and wrinkles reveal your unique personality and tell your life’s story. But they can also create an angry, sad or aged appearance — especially when they form between your brows. If you want your features to reflect how you truly feel about yourself, you may want to consider wrinkle reduction with Jeuveau®.

This next-generation neuromodulator was FDA-approved for treating frown lines between the brows, also called glabellar lines. Jeuveau® contains a neurotoxin that prevents specific facial muscles from moving and causing wrinkles. As a new product on the market, it has a couple of advantages over other wrinkle relaxers that make it a popular option.

Jeuveau® can also be combined with other cosmetic procedures to create a more youthful appearance.

What Is Jeuveau®?

Jeuveau® is a wrinkle-relaxing injection developed by Evolus, inc, a South Korean pharmaceutical company. When injected into the muscles of the face, the product temporarily improves the appearance of moderate to severe wrinkles. Popularly called “Newtox,” it is a novel alternative to older wrinkler relaxers.

It was FDA-approved in 2019 for the treatment of glabellar lines in adults. It is currently not used to treat medical conditions like other neuromodulators. The results from Jeuveau® can last up to six months. And with regular touch-up appointments, you can enjoy the results indefinitely. Because the product is not used to treat medical conditions, it is available at a lower price compared to its competitors.

Jeuveau® has been tested in over 2,000 patients in the European & Canadian phase III clinical trial. It was proven to be safe and effective in diminishing moderate to severe glabellar wrinkles.

How Does Jeuveau® Work?

One of the reasons we develop wrinkles is facial movement. Smiling, frowning, squinting and other facial expressions cause our skin to crease and develop permanent furrows. Jeuveau® works by preventing the muscles that contribute to these wrinkles from moving. Over time, this causes wrinkles to diminish and stops them from forming again.

The active ingredient in Jeuveau® is purified prabotulinumtoxinA-xvfs, a type of botulinum toxin and the active ingredient of all other injectable wrinkle relaxers.


Botulinum toxin is a neurotoxin produced by the bacterium Clostridium botulinum. It temporarily prevents the release of nerve signals in muscles, which causes the muscles to stop contracting until the treatment wears off.

The effects of Jeuveau® can last four to six months on average. Once the effects of this treatment wear off, wrinkles begin to reappear. This is why regular injections at intervals of three to four months are required.


Jeuveau® is a next-generation neuromodulator (wrinkle-relaxer) that comes with a number of benefits:

  • Clinically tested for safety and efficiency
  • Quick and no-downtime treatment
  • Long-lasting wrinkle reduction
  • Results become visible after two days
  • More affordable than competitors

Paired Procedures





Dermal Fillers

Dermal Fillers

Frequently Asked Questions

What Can Jeuveau® Treat?

Jeuveau® is currently approved only for the treatment of glabellar lines, also called frown lines or 11s. Those are the two vertical lines that form between your eyebrows. This popular injectable can diminish the appearance of moderate to severe frown lines in anyone over the age of 18. While the product can be used to treat other wrinkles in the face, this would be considered off-label use.

How do I prepare for Jeuveau®?

For Jeuveau®, you may need to start preparing a week before treatment. Avoid blood-thinning medicines and supplements, like NSAIDs, fish oil, vitamin E and Ginkgo Biloba. This is to help minimize bruising and bleeding at the injection site. Also, avoid alcohol on the night before treatment.

What happens during a Jeuveau® treatment?

Your provider will remove any makeup covering the treatment area and cleanse your skin. Using a fine-gauge needle, they will inject the product into various different sites around your frown lines. The whole procedure should take about 15 minutes from start to finish. You will be allowed to apply makeup and go about your day as usual.

What are the results with Jeuveau®?

After about two days, you will begin to notice a smoother appearance between your eyebrows. Your wrinkles will gradually diminish over the next few days, with the full effect taking place after a week.

Are there any side effects with Jeuveau®?

The most common side effects reported with Jeuveau® are headache, eyelid droop, increases in white blood cell numbers or cold-like symptoms. However, side effects are rare. There also may be bruising and swelling at the treatment site, which should subside within a week. Some clients can also develop allergic reactions to the ingredients.

Is Jeuveau® better than BOTOX® Cosmetic?

Jeuveau® is different from BOTOX®, and both products have their unique benefits. BOTOX® is approved for the treatment of frown lines, forehead lines and crow’s feet, whereas Jeuveau® is approved only for glabellar lines. However, BOTOX® can cost more, especially in the long run. Both products have the same level of efficiency and comparable duration.

How many Jeuveau® injections will I need?

Most clients need three to five injections in one session to treat their glabellar lines. This equates to 10 to 20 units. How many units or injections you should get depends on your facial features and how active your facial muscles are.

Can I combine Jeuveau® with dermal fillers?

Yes! If you want to rejuvenate your face with injections, we can create a treatment plan that combines Jeuveau® with dermal fillers like Restylane or Juvéderm.

Does Jeuveau® hurt?

Jeuveau® is administered using fine-gauge needles, which you will barely feel. Most clients feel a quick pinch and find this treatment quite tolerable.

See Your Glabellar Lines Disappear With Jeuveau® at The Lifestyle Center

At The Lifestyle Center in the Ladue-Frontenac area of St. Louis, we aim to provide our clients with cutting-edge cosmetic treatments that will make them feel better about their appearance. With our holistic approach, we want to help you choose the best procedures for your unique cosmetic goals.

Schedule your Jeuveau® consultation to see if this injectable wrinkle treatment is the right choice for you.

Learn More

More than 30 FDA-approved medical devices

A professional staff with over 70 years of combined experience in the aesthetic industry

Unmatched variety of procedures and treatments

Medical Director on-site daily

Discover Your Ideal Aesthetic Treatments With Our Virtual Consultation Tool

This innovative platform is designed to help you find the aesthetic procedures that best align with your aesthetic needs. Get personalized treatment recommendations and valuable insights into your options so you can make informed decisions to reach your goals.

  • Available 24/7
  • No Cost
  • No Commitment
  • Private and Confidential

Start my Virtual Consultation